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ASCP ASCP-MLT Exam Syllabus Topics:
| Section | Weight | Objectives |
|---|---|---|
| Laboratory Operations | 5–10% | - Instrumentation and laboratory mathematics - Quality assessment and safety |
| Hematology | 20–25% | - Laboratory testing and hemostasis - Physiology and disease states |
| Blood Banking | 15–20% | - Transfusion practice and testing - Blood products and components - Blood group systems and immunology |
| Immunology | 5–10% | - Principles of immunology - Serologic procedures and immune diseases |
| Chemistry | 20–25% | - Carbohydrates, lipids, and enzymes - Electrolytes, acid-base, and toxicology |
| Microbiology | 15–20% | - Bacteriology and mycology procedures - Virology and parasitology testing |
| Urinalysis and Other Body Fluids | 5–10% | - Physical and chemical testing - Microscopic analysis and disease correlation |
ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:
1. A positive DAT is consistent with a diagnosis of hemolytic disease of the newborn. A hemoglobin performed on the cord blood serves as an indicator of the severity of the disease.
In order to detect the presence of antibodies fixed on the RBC's of newborns one should:
A) Test the baby's cells with typing antiserum
B) Perform a direct antiglobulin test (DAT) on the cord blood
C) Perform an indirect antiglobulin test (IAT) on the cord blood
D) Look for agglutination in a mixture of mother's serum and baby's cells
2. Healthcare workers that worked closely with patient specimens were at an increased risk of contracting which viral infection before a vaccine was developed?
A) HIV
B) Hepatitis C
C) Hepatitis A
D) Hepatitis B
3. In this case, with the pre-incubation aPTT mixing study result "corrected" and the post-incubation aPTT mixing study result "not corrected", a coagulation inhibitor should be suspected. Both anti-factor VIII and lupus anticoagulant have been known to be slow-acting and can exhibit this result pattern. If a factor deficiency was present, we should not see a post-incubation prolongation.
Hematology
What may cause the following mixing studies results?
Initial aPTT = 133 seconds
1:1 Mix aPTT pre-incubation = 33 seconds
1:1 Mix aPTT post-incubation = 124 seconds
A) A slow acting coagulation inhibitor
B) Factor XI deficiency
C) Factor IX deficiency
4. As magnification DECREASES, the opening of the iris diaphragm will...
A) decrease (get smaller)
B) increase (get bigger)
C) stay the samel
5. Immunology
The immunoglobulin molecule is made up of both heavy and light chains - the light chains can be comprised of which of the following:
A) Alpha or beta
B) Alpha or lambda
C) Kappa or beta
D) Kappa or lambda
Solutions:
| Question # 1 Answer: B | Question # 2 Answer: D | Question # 3 Answer: A | Question # 4 Answer: A | Question # 5 Answer: D |
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